There are five stages of renal failure. Creatinine level in blood is the obvious changes in each stages of renal failure. Different symptoms can also present in different stages. Take a look.
Creatinine level and symptoms in five stages of kidney disease
In Stage 1 & 2, the creatinine level is <133umol/l (<1.5mg/dl) and generally there is no symptom.
In Stage 3, the creatinine level is 133~221 (1.5-2.5). Patients will have tiredness, anemia and frequent night urine.
In Stage 4, the creatinine level is 221~442 (2.5-5.0). In this stage, there will be obvious anemia, nausea, vomiting, metabolic acidosis and electrolytes disorder.
In stage 5, the creatinine level is >442 (>5.0). There will be obvious symptoms of renal failure such as severe anemia, digestive tract symptoms, nervous symptoms, water, electrolytes and acid-base imbalance.
The increase of creatinine level in blood is related to kidney function damages. The more kidney function damages, the higher the creatinine will be. Creatinine level in blood is a main index that reflects the renal function. But we need to point out that creatinine begins to increase when about 50% of kidney function has damaged. Hence it is advisable to test your kidney function regularly to detect it early. Kidney function can be tested by urine test, chemical examination, and blood test. The normal test content include urine sample, USG, microscopic examination of urinary sediment, urea nitrogen, creatinine, NPN(Non-Protein Nitrogen), phenol red excretion test, etc. Some substances such as lead (Pb), mercury (Hg), cadmium (Cd), chromium, arsenic (As), petroleum products can also lead to damages of kidney.
Kidney function damages can be detected in early stages
In early stage, kidney function damages can lead to microalbuminuria. If the microalbuminuria is more than 20μg /ml, it indicates your kidney function has damaged. It is advisable to receive treatment to prevent developing of the disease.